sv40 viruses การใช้

• Psoralen crosslinks in virus DNA also appear to be removed by a recombinational repair process as occurs in SV40 virus infected cells, and in herpes simplex virus infected cells.
• Fears about a potential threat from the virus heightened in 1994 when researchers studying a type of lung cancer thought to be caused only by asbestos discovered many of the cancers contained the SV40 virus.
• This system utilized the virus-encoded T antigen that binds to the SV40 virus origin of DNA replication, the start site for DNA synthesis, coupled with purified human proteins, many of them discovered by Stillman and his colleagues.
• It belongs to the murine polyomavirus group, one of the three main clades of polyomaviruses . ( The group is named for murine polyomavirus, the earliest virus of the group to be discovered, and does not imply that MCV is transmitted to humans from rodents . ) Although it has been confused with the controversial SV40 virus in some blog postings, it is a completely distinct virus.